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Fire destroys barn, vehicle in Cross Creek
Dec 29, 2025
Multiple fire units responded to a vehicle and barn fire in Cross Creek on Sunday night. According to an Alachua County Fire Rescue (ACFR) release, firefighters […]
Referendums and reveals: Mainstreet’s top 10 local news stories of 2025
Dec 29, 2025
Mainstreet published more than 2,000 stories in 2025 to keep local residents in the know, so you can stay safe, cast informed votes and be a better neighbor in Gainesville, Alachua County and around North […]
Gainesville activates Cold Night Shelter for Dec. 29 to Jan. 1
Dec 29, 2025
The city of Gainesville will activate its Cold Night Shelter Program (CNS) as temperatures are projected to drop below 45 degrees Fahrenheit on the nights of […]
State champion highlights All Area golf teams
Dec 29, 2025
There was one area individual state champion in golf this past fall. That was senior Ryan Donaldson of Suwannee (Live Oak), who placed first at the […]
Morriston teen dies in ATV crash in Levy County
Dec 26, 2025
Driver overturns vehicle on Friday afternoon.
Fort White man arrested for shooting person in head
Dec 26, 2025
Suspect charged with attempted second-degree murder.
Unexpected UF finding could offer new treatment for meth addiction
Dec 26, 2025
Study led by McKnight Brain Institute team.
2025 brings breakthroughs in Alzheimer’s diagnosis and treatment
Dec 26, 2025
For the millions of Americans touched by Alzheimer’s disease, 2025 brought major advances in the understanding of brain health and progress in diagnosis and treatment. Here […]
4 candidates announce runs for Alachua County School Board seats in 2026
Dec 26, 2025
Three seats are up for reelection.
AI-powered tool helps UF students find creative math solutions
Dec 26, 2025
New tool called HallMos developed by UF professor.
SUV hits, kills Old Town man, 30, walking on CR 349 in Dixie County
Dec 26, 2025
Incident occurs on Wednesday evening.
Aging Matters: How seniors deal with total knee arthroplasty in U.S.
Dec 26, 2025
Nearly 800,000 knee and 450,000 hip replacements are performed annually.
UF study says dollar stores may increase food deserts
Dec 25, 2025
Study published in American Journal of Agricultural Economics.
Gainesville’s bird count sees 171 species despite drought
Dec 25, 2025
Birders had chance to tie record.
UF: Debate finished over diet safety for cancer patients
Dec 25, 2025
New study published in Journal of Clinical Oncology.
Alachua Arts Council opens applications for 2026 Artists Conference
Dec 25, 2025
Deadline to present in or sponsor conference is Jan. 16.
Alachua County unveils food hub feasibility study webpage
Dec 25, 2025
Microsite to offer residents updates throughout 30-month initiative.
Holiday History: Christmas and record keeping
Dec 25, 2025
Christians believe Jesus’ birth was fulfillment of prophecy.
Gainesville to celebrate U.S.’s 250th anniversary with ‘Six Triple Eight’ performance
Dec 24, 2025
Performances slated for January at Gainesville Old Post Office.
New postal rule may affect charitable gift postmarks for 2025 tax year
Dec 24, 2025
Postal Service no longer applying postmarks at post offices and mailboxes.
529 education savings plans: More flexible than you think
Dec 24, 2025
Planning for your child’s education can feel overwhelming, but a 529 education savings plan offers a powerful way to build a financial foundation for their educational future.
Ode to Old Florida: Huff family reflects on Orange Lake Overlook’s citrus legacy
Dec 24, 2025
Alachua Conservation Trust nears $500K goal for preserve renovations.
